​
A. Requires all three of the following findings.​

​​​​​​​​​​​​​​​​​​​​1. Documentation of all three facial abnormalities (smooth philtrum, thin vermillion, and small

     palpebral fissures)
2. Documentation of growth deficits
3. Documentation of CNS abnormality

​
B. Facial dysmorphia. Based on racial norms, individual exhibits all three characteristic facial features:

1. Smooth philtrum (University of Washington Lip-Philtrum Guide rank 4 or 5)
2. Thin vermillion border (University of Washrngton Lip-Philtrum Guide rank 4 or 5)
3. Small palpebral fissures (at or below 1Oth percentile )

​
C. Growth problems.

Confirmed prenatal or postnatal height or weight, or both, at or below the 10th percentile, documented at any one point in time (adjusted for age, sex, gestational age, and race or ethnicity).

D. Central nervous svstem abnormalities​

Structural

• Head circumference (OFC) at or below the 1Oth percentile adjusted for age and sex.
• Clinically significant brain abnormalities observable through imaging.
   

​Neurological
​​​​​​​​​​Neurological problems not due to a postnatal insult or fever, or other soft neurological signs
outside normal limits.

​
Functional​
Performance substantially below that expected for an individual's age, schooling, or
circumstances, as evidenced by:

1. Global cognitive or intellectual deficits representing multiple domains of deficit (or
     significant developmental delay in younger children) with performance below the 3rd
     percentile (2 standard deviations below the mean for standardised testing)

OR

​2. Functional deficits below the 16th percentile (1 standard deviation below the mean for
    standardised testing) in at least three of the following domains:

• Cognitive or developmental deficits or discrepancies
• Executive functioning deficits
• Motor functioning delays
• Problems with attention or hyperactivity
• Poor social skills
• Other (e.g., sensory problems, pragmatic language problems, or memory deficits)

​
E. Maternal Alcohol Exposure

​
1. Confirmed prenatal alcohol exposure
2. Unknown prenatal alcohol exposure

​

​

Source: Adapted from Bertrand,J., Floyd, R. L., Weber, M. K., O'Connor, M., Riley, E. P.,Johnson, K. A., Cohen, D. E., & National Task Force on FAS/FAE. Fetal alcohol syndrome: Guideiines for referral and diagnosis. Atlanta, GA: Centers for Disease Control and Prevention;2004.

​

See:  www.cdc.gov/ncbddd/fasd/documents/fas_guidelines_accessible.pdf​​